Curcumin : 400 milligrams (mg) twice a day, lessens inflammation in the body, which in turn eases joint pain and stiffness. Yet has the advantage of not causing the side effects of NSAIDs.
Boswellia : 150 mg of boswellic acids three times per day ( also known as frankincense) eases inflammation and improves blood supply to the joints. For those with joint pain from OA or RA, boswellia improves morning pain and stiffness, joint flexibility, and swelling. The combination of curcumin and boswellia has been compared to the prescription drug Celebrex in people with knee OA with similar outcome in both groups.
Comfrey cream : apply topically to areas of pain two to four times daily, as needed. Topical comfrey provides excellent relief for arthritis pain, with a key benefit being how quickly it works. “Comfrey cream has been on the European market for more than 20 years, with 14 published studies proving its effectiveness at reducing pain and inflammation and stimulating healing.”
Omega-3 essential fatty acids : Up to 2.6 grams, twice a day, of EPA/DHA. Fish oil is an excellent source of omega-3 fatty acids such as EPA and DHA. Omega 3s reduce inflammation, including in the joints. Omega 3s significantly reduce the joint tenderness and morning stiffness of RA and the pain of those with knee OA.
Probiotics: Eighty percent of our immune cells reside in the gut, where bacteria actively regulates the immune defenses. Studies have found that the onset of rheumatoid arthritis elates to the loss of beneficial gut bacteria, and probiotics can reduce symptoms of this form of arthritis. Other studies have found that probiotics reduce inflammation in healthy young adults and seniors. Helpful strains include Lactobacillus salivarius, L.gasseri, Bifidobacterius bifdum, and B. longum.
Source: “Benefits of Antioxidant Supplements for Knee Osteoarthritis: Rationale and Reality” by A.K. Grover and S.E. Samson, Nutr J 1/5/16 .